Endogenous methods

Accurate detection of GM events by PCR requires the use of appropriate controls.

One such control is a taxon-specific assay that amplifies a specific sequence of known copy number and
demonstrates no allelic variation in the host plant genome, also referred to as an endogenous
method.

CropLife International member companies (BASF, Bayer, Corteva, and Syngenta) have
chosen to make a number of validated endogenous methods publicly available, to support
global harmonization of detection methods, to reduce development costs for academics and
small/medium enterprises and to ensure that the CropLife International Detection Methods
Database remains a comprehensive and trusted resource for detection methods.